Okami HD on PlayStation 3 opens with a tale of the goddess Shiranui, a white wolf, who teams up with the great swordsman Nagi to fight an eight-headed demon called Orochi that plagues Kamiki village. Unable to defeat the beast, Shiranui and Nagi seal away the evil, but the wolf goddess is poisoned and dies. In honour of the heroism of the wolf, the villagers create a shrine and place a statue of Shiranui within it.
One hundred years later, a boastful descendant of Nagi, breaks Orochi's seal to prove the legend is a lie, but instead the evil force escapes and once again a curse falls upon the whole of Nippon.
To fight this darkness, Sakuya, the wood sprite protector of Kamiki Village, uses her remaining strength to bring back the sun goddess and the wolf statue springs to life.
Armed with a celestial brush as Amaterasu, the reincarnated sun goddess, you must travel across Nippon to bring peace and tranquillity and defeat the evil of Orochi.